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ALLEGRA D       

      Allegra-D is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children 12 years of age and older. Symptoms treated effectively include sneezing, rhinorrhea, itchy nose/palate/ and/or throat, itchy/watery/red eyes, and nasal congestion.

How Taken
The recommended dose of Allegra-D is one tablet twice daily for adults and children 12 years of age and older. It is recommended that the administration of Allegra-D with food should be avoided. A dose of one tablet once daily is recommended as the starting dose in patients with decreased renal function.

Warnings/Precautions
Do not take Allegra-D if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days; asthma or another lung disease; diabetes; thyroid problems; glaucoma or increased pressure in the eye; urinary retention or an enlarged prostate; kidney or liver disease; or heart disease, high blood pressure, or an irregular heartbeat. You may not be able to take Allegra-D, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Allegra-D is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take Allegra-D without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known if Allegra-D passes into breast milk. Do not take Allegra-D without first talking to your doctor if you are breast-feeding a baby. Allegra-D is not approved for use by children younger than 12 years of age.

Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Possible Side Effects
Nausea, stomach upset, trouble sleeping, headache, or cold symptoms may occur. If these persist or worsen, notify your doctor promptly. Unlikely but report promptly: dizziness, mental/mood changes, fast heartbeat, fever. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, irregular heartbeat. Although drowsiness is very uncommon at usual doses under normal circumstances, be aware that drowsiness may occur and may affect the ability to perform tasks requiring alertness (e.g., driving). If you notice other effects not listed above, contact your doctor or pharmacist.

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Sleep Apnea May Herald Early Heart Disease.
         The snoring and constant awakenings of severe sleep apnea could provide an early indication of heart disease, researchers report. Brazilian researchers detected early hardening of the arteries in 42- to 44-year-old patients with severe obstructive sleep apnea, despite the absence of overt signs of cardiovascular disease. People with obstructive sleep apnea repeatedly stop breathing in their sleep as a result of partial or complete blockage of the upper airway. The vascular abnormalities detected by researchers correlated significantly with the severity of the patient's sleep apnea, noted lead researcher Dr. Luciano F. Drager of the Heart Institute at the University of Sao Paulo Medical School.
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