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ESTRADIOL       

      Use Estrandiol to reduce moderate to severe menopausal symptoms, to treat vulval and vaginal atrophy, treat certain cancers in special situations and prevent the thinning of bones.

How Taken
Talk to your local physician or pharmacist. You and your doctor should reevaluate whether or not you still need estrogens at least every six months.

Warnings/Precautions
If you think you may be pregnant, do not use any form of estrogen-containing drug. Using Estrandiol while you are pregnant may cause your unborn child to have birth defects. Estrandiol does not prevent miscarriage.

Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Possible Side Effects
The following side effects have been reported with use of this medicine: nausea and vomiting; breast tenderness or enlargement; enlargement of benign tumors; retention of excess fluid (this may make some conditions worsen, such as asthma, epilepsy, migraine, heart disease, or kidney disease); a spotty darken of the skin, particularly on the face.

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Implanted Nerve Stimulator Eases Epilepsy in Kids.
         Stimulation of a cranial nerve through an implant can effectively treat some children with epilepsy, according to the results of a new two-year study. In a study of more than 75 young patients, doctors found that 59 percent of those implanted with a vagus nerve stimulator did not suffer from localization-related epilepsy, or seizures occurring in one part of the brain. Hospital visits for epilepsy-related conditions also decreased by 41 percent, the researchers reported Wednesday at the International League Against Epilepsy Congress in Paris. The nerve stimulator is implanted in the left side of a patient's neck and works by sending signals to the brain to decrease the electrical activity that leads to seizures. It was approved by the U.S. Food and Drug Administration in 1997 for the treatment of epilepsy unresponsive to medication.
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